Understanding Neurodegenerative and Rare Diseases at the Molecular Level
This research line investigates the molecular basis of rare and neurodegenerative diseases, focusing on how protein misfolding, impaired intracellular trafficking, and metal ion dysregulation disrupt proteostasis and drive pathology. The programme addresses disorders including amyloidosis, myopathies, metabolic diseases, ALS, with the aim of elucidating disease mechanisms at the molecular level and identifying novel therapeutic strategies targeting protein structure and cellular homeostasis.